Pre-doctorate position in the frame of the project SEVEN / Screening metastasis targeting properties of extracellular vesicle’s biomolecular corona for Engineering therapeutic biomimetic nanoparticle

EURAXESS hosting organisation · عدة بلدان أوروبية

Project description: The nanoengineering of inorganic/organic nanoparticles (NPs) with natural signaling carriers such as extracellular vesicles (EVs) is a promising tool to address the lack of treatment efficiency of currently available therapies in oncology, blamed on the insufficient accumulation of the antitumoral molecules in the metastasis tissues. Despite several years of intense efforts, therapeutic EVs are still far away from clinical practice. Recent studies have evidenced that this failure is due to the lack of knowledge on how EVs behave in biological environments and how their therapeutic cargo affects the metastasis targeting moieties present on their membranes. Seven believes that the lack of attention on the unknown biomolecular corona (BC) and on its role governing the EVs

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